Coagulase

Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.

Also Known As:

Clumping Factor (Staphylococcal); Staphylococcus aureus clone pSCa2 of Coagulase; Staphylococcus aureus strain 213 of Coagulase; Staphylococcus aureus strain 8325-4 of Coagulase; Clumping Factor, Staphylococcal; Factor, Staphylococcal Clumping; Staphylococcus aureus strain 8325 4 of Coagulase; Staphylocoagulase; Staphylococcal Clumping Factor

Pharmalogical Action Categories:

Coagulants

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Hydrolases: 2206
    - Peptide Hydrolases: 24289
      - Endopeptidases: 643
        Coagulase: 3759
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Bacterial Proteins: 401
    - Coagulase: 3759

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Disease

Drug/Important Bio-Agent (IBA)